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Dashlaali, Helma, moslehishad, maryam, Ghamari, Fatemeh, Mohammadi, mohammad. (1404). The synergistic effects of Moringa Peregrina and Murraya Koenigii koenigii leaf extracts on antimicrobial activity (against Candida albicans and Helicobacter pylori), antioxidant, and lipase inhibitory properties. , (), -. doi: 10.22059/jfabe.2025.388109.1195
Helma Dashlaali; maryam moslehishad; Fatemeh Ghamari; mohammad Mohammadi. "The synergistic effects of Moringa Peregrina and Murraya Koenigii koenigii leaf extracts on antimicrobial activity (against Candida albicans and Helicobacter pylori), antioxidant, and lipase inhibitory properties". , , , 1404, -. doi: 10.22059/jfabe.2025.388109.1195
Dashlaali, Helma, moslehishad, maryam, Ghamari, Fatemeh, Mohammadi, mohammad. (1404). 'The synergistic effects of Moringa Peregrina and Murraya Koenigii koenigii leaf extracts on antimicrobial activity (against Candida albicans and Helicobacter pylori), antioxidant, and lipase inhibitory properties', , (), pp. -. doi: 10.22059/jfabe.2025.388109.1195
Dashlaali, Helma, moslehishad, maryam, Ghamari, Fatemeh, Mohammadi, mohammad. The synergistic effects of Moringa Peregrina and Murraya Koenigii koenigii leaf extracts on antimicrobial activity (against Candida albicans and Helicobacter pylori), antioxidant, and lipase inhibitory properties. , 1404; (): -. doi: 10.22059/jfabe.2025.388109.1195

The synergistic effects of Moringa Peregrina and Murraya Koenigii koenigii leaf extracts on antimicrobial activity (against Candida albicans and Helicobacter pylori), antioxidant, and lipase inhibitory properties

Journal of Food and Bioprocess Engineering
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 17 خرداد 1404
نوع مقاله: Original research
شناسه دیجیتال (DOI): 10.22059/jfabe.2025.388109.1195
نویسندگان
Helma Dashlaali1؛ maryam moslehishad* 2؛ Fatemeh Ghamari3؛ mohammad Mohammadi4
1Department of Food Science and Technology, Medical Branch, Islamic Azad University, Tehran, Ira
2Department of Food Science & Technology, Safadasht Branch, Islamic Azad University, Tehran, Iran
3Department of Science Payame Noor University, P.O.Box 19395-4697,Iran
4Assistant professor Department of science payame noor university ,P.O.Box 19395-4697,Tehran,Iran
چکیده
ABSTRACT

This research aimed to evaluate the antimicrobial, antioxidant, and lipase inhibitory properties of leaf extracts from Moringa Pergerinaperegrina (M. peregrina) and Murraya koenigii (M. koenigii). Antioxidant capacity was assessed using the ABTS method, while total phenol content was measured via the Folin-Ciocalteu method. The antifungal activity against Candida albicans was determined through zone inhibition assays, and the ability to inhibit Helicobacter pylori was evaluated by measuring urease enzyme activity. Lipase activity inhibition was assessed using ELISA at 405 nm. Analysis of variance revealed that increasing concentrations of both extracts significantly enhanced antioxidant activity and total phenol content (p<0.05). MoringaM. peregrinaPergerina and M. koenigiiMurraya koenigii exhibited the highest antioxidant activity at 4000 mg/L, while M. koenigiiMurraya koenigii showed the lowest activity at 31.25 mg/L. The highest total phenol content occurred at 4000 ppmmg/L for M. koenigiiMurraya koenigii. Synergistic effects of both extracts were noted at 1000 ppmmg/L. At 1500 ppmmg/L, MoringaM. peregrinaPergerina displayed the largest inhibition zone against Candida albicans; conversely, M. koenigiiMurraya koenigii showed the strongest inhibition of Helicobacter pylori at 2000 ppmmg/L. The greatest lipase inhibitory activity was found at 4000 ppmmg/L for MoringaM. peregrinapergerina, while M. koenigiiMurraya koenigii had the least at 2000 ppmmg/L, and there were no synergistic effects. These findings suggest that MoringaM. peregrinapergerina and M. koenigiiMurraya koenigii leaf extracts have potential applications in developing anti-diabetic food products.
کلیدواژه‌ها
Antibacterial Activity؛ Antioxidant؛ Lipase Inhibitory؛ Murraya koenigii؛ Moringa peregrina
آمار
تعداد مشاهده مقاله: 36





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