The synergistic effects of Moringa Peregrina and Murraya koenigii leaf extracts on antimicrobial activity (against Candida albicans and Helicobacter pylori), antioxidant, and lipase inhibitory properties | ||
| Journal of Food and Bioprocess Engineering | ||
| دوره 7، شماره 2، اسفند 2024، صفحه 84-92 اصل مقاله (792.75 K) | ||
| نوع مقاله: Original research | ||
| شناسه دیجیتال (DOI): 10.22059/jfabe.2025.388109.1195 | ||
| نویسندگان | ||
| Helma Dashtlali1؛ Maryam Moslehishad* 2؛ Fatemeh Ghamari3؛ Hamed Mohammadi4 | ||
| 1Department of Food Sciences & Technology, TeMS.C., Islamic Azad University, Tehran, Iran | ||
| 2Department of Food Science and Technology, ShQ. C., Islamic Azad University, Shahr-e Qods, Iran | ||
| 3Department of Science, Payame Noor University, Tehran, Iran | ||
| 4Department of Agriculture, Payame Noor University, Tehran, Iran | ||
| چکیده | ||
| This research aimed to evaluate the antimicrobial, antioxidant, and lipase inhibitory properties of leaf extracts from Moringa peregrina (M. peregrina) and Murraya koenigii (M. koenigii). Antioxidant capacity was assessed using the ABTS method, while total phenol content was measured via the Folin-Ciocalteu method. The antifungal activity against Candida albicans was determined through zone inhibition assays, and the ability to inhibit Helicobacter pylori was evaluated by measuring urease enzyme activity. Lipase activity inhibition was assessed using ELISA at 405 nm. Analysis of variance revealed that increasing concentrations of both extracts significantly enhanced antioxidant activity and total phenol content (p<0.05). M. peregrina and M. koenigii exhibited the highest antioxidant activity at 4000 mg/L, while M. koenigii showed the lowest activity at 31.25 mg/L. The highest total phenol content occurred at 4000 mg/L for M. koenigii. Synergistic effects of both extracts were noted at 1000 mg/L. At 1500 mg/L, M. peregrina displayed the largest inhibition zone against Candida albicans; conversely, M. koenigii showed the strongest inhibition of Helicobacter pylori at 2000 mg/L. The greatest lipase inhibitory activity was found at 4000 mg/L for M. peregrina, while M. koenigii had the least at 2000 mg/L, and there were no synergistic effects. These findings suggest that M. peregrina and M. koenigii leaf extracts have potential applications in developing anti-diabetic food products. | ||
| کلیدواژهها | ||
| Antibacterial activity؛ Antioxidant؛ Lipase inhibitory؛ Murraya koenigii؛ Moringa peregrine | ||
| مراجع | ||
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