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Novel Three-Step Synthesis of Imidazo[1,2-c]quinazoline-5(6H)-thione Derivatives | ||
Journal of Sciences, Islamic Republic of Iran | ||
مقاله 2، دوره 29، شماره 1، فروردین 2018، صفحه 21-25 اصل مقاله (248.75 K) | ||
نوع مقاله: Final File | ||
شناسه دیجیتال (DOI): 10.22059/jsciences.2018.64790 | ||
نویسندگان | ||
S. Nahavandian؛ S. Allameh* | ||
Department of Chemistry, Faculty of Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Islamic Republic of Iran | ||
چکیده | ||
A novel synthesis of Iimidazo[1,2-c]quinazoline-5(6H)-thione framework was developed through a three-step reaction starting from benzil. The resulting (2-nitrophenyl)-4,5-diphenyl-1H-imidazole from the reaction of benzil and different 2-nitrobenzaldehyde, reduction of nitro group and then cyclization reaction with carbon disulfide (CS2). All steps were carried out under easy and user-friendly conditions in short time without using expensive catalysts or reagents. | ||
کلیدواژهها | ||
Iimidazo[1,2-c]quinazoline-5(6H)-thione؛ Heterocycles؛ 2-Nitrobenzaldehydes؛ Carbon disulfide (CS2) | ||
مراجع | ||
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