Novel Three-Step Synthesis of Imidazo[1,2-c]quinazoline-5(6H)-thione Derivatives | ||
| Journal of Sciences, Islamic Republic of Iran | ||
| مقاله 2، دوره 29، شماره 1، بهار 2018، صفحه 21-25 اصل مقاله (248.75 K) | ||
| نوع مقاله: Final File | ||
| شناسه دیجیتال (DOI): 10.22059/jsciences.2018.64790 | ||
| نویسندگان | ||
| S. Nahavandian؛ S. Allameh* | ||
| Department of Chemistry, Faculty of Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Islamic Republic of Iran | ||
| چکیده | ||
| A novel synthesis of Iimidazo[1,2-c]quinazoline-5(6H)-thione framework was developed through a three-step reaction starting from benzil. The resulting (2-nitrophenyl)-4,5-diphenyl-1H-imidazole from the reaction of benzil and different 2-nitrobenzaldehyde, reduction of nitro group and then cyclization reaction with carbon disulfide (CS2). All steps were carried out under easy and user-friendly conditions in short time without using expensive catalysts or reagents. | ||
| کلیدواژهها | ||
| Iimidazo[1,2-c]quinazoline-5(6H)-thione؛ Heterocycles؛ 2-Nitrobenzaldehydes؛ Carbon disulfide (CS2) | ||
| مراجع | ||
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آمار تعداد مشاهده مقاله: 880 تعداد دریافت فایل اصل مقاله: 884 |
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