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اثر مکمل چربی امگا-3 و تعداد دفعات خوراک بر متابولیسم گلوکز و انسولین در بزغالههای مهابادی | ||
| مجله تحقیقات دامپزشکی (Journal of Veterinary Research) | ||
| مقاله 7، دوره 71، شماره 4، دی 1395، صفحه 415-422 اصل مقاله (407.18 K) | ||
| شناسه دیجیتال (DOI): 10.22059/jvr.2016.59997 | ||
| نویسندگان | ||
| سارا عطایی نظری1؛ مهدی گنج خانلو* 2؛ ابوالفضل زالی3؛ منوچهر امینی4 | ||
| 1گروه تغذیه دام، پردیس کشاورزی و منابع طبیعی دانشگاه تهران،کرج، ایران | ||
| 2استاد پردیس کشاورزی و منابع طبیعی دانشگاه تهران | ||
| 3گروه علوم دام، پردیس کشاورزی و منابع طبیعی دانشگاه تهران،کرج، ایران | ||
| 4دانشکده دامپزشکی دانشگاه تهران، تهران، ایران | ||
| چکیده | ||
| زمینه مطالعه: تحقیقات گذشته نشان داده امگا-3 و سطوح بالا مصرف خوراک تأثیر مثبت بر حساسیت به انسولین در بافت‌ها داشته است. هدف: این مطالعه به منظور بررسی اثر مکمل چربی امگا-3 بر متابولیسم گلوکز و انسولین در بزغالههای مهابادی انجام شد. روش کار: تعداد 28 راس بزغاله مهابادی (3 تا 4 ماهه با میانگین وزن اولیه kg 5± 17) در قالب طرح فاکتوریل با 4 تیمار مورد استفاده قرار گرفتند. جیره پایه یکسان بود و بزغاله‌ها با 4 تیمار، 1) اشباع دو بار در روز، 2) اشباع چهار بار در روز، 3) دو در صد مکمل امگا-3 دو بار در روز، 4) دو در‌صد مکمل امگا-3 چهار بار در روز ، به صورت انفرادی به مدت 90 روز تغذیه شدند. در روز 70 تست تحمل گلوکز وریدی بعد 20 ساعت محرومیت غذایی انجام شد. نمونه‌گیری از خون در زمان‌های 15-،10-،5-،5، 10،15، 20، 30، 45، 60، 120، 180 انجام شد و داده‌ها با استفاده از نرم افزار SAS آنالیز شدند. نتایج: در این آزمایش مکمل امگا-3 بر روی نرخ زدودگی گلوکز(CR) اثر معنی‌داری داشت (0.05>p). از طرفی افزایش تعداد دفعات خوراک اثر معنی‌داری بر روی نرخ زدودگی گلوکز (CR) و زمان رسیدن به نصف غلظت حداکثر گلوکزداشت (0.05>p). افزایش تعداد دفعات خوراک باعث معنی‌دار شدن پاسخ به انسولین گردید (0.05>p). نتیجه‌گیری نهایی: این آزمایش نشان می‌دهد که مصرف مکمل امگا-3 در سطح تغذیه‌ای بالا باعث بهبود وضعیت متابولیسم گلوکز و انسولین می‌گردد. | ||
| کلیدواژه‌ها | ||
| امگا-3؛ بزغاله مهابادی؛ تعداد دفعات خوراک؛ حساسیت به انسولین؛ نرخ زدودگی گلوکز | ||
| عنوان مقاله [English] | ||
| Effects of omega-3 fat supplementation and feeding frequency on glucose metabolism and insulin in on Mahabad kid | ||
| نویسندگان [English] | ||
| Sara Attaee-Nazari1؛ Mehdi Ganjkhanlou2؛ Abolfazl Zali3؛ Manoochehr Amini4 | ||
| 1Department of Animal Sciences, Faculty of Agricultural Sciences and Engineering, University of Tehran, Karaj, Iran | ||
| 2Department of Animal Sciences, Faculty of Agricultural Sciences and Engineering, University of Tehran, Karaj, Iran | ||
| 3Department of Animal Sciences, Faculty of Agricultural Sciences and Engineering, University of Tehran, Karaj, Iran | ||
| 4Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran | ||
| چکیده [English] | ||
| BACKGROUND: Previous studies have shown that high intake and level of omega-3 have a positive impact on insulin sensitivity in the tissues. OBJECTIVES: This study investigated the effect of omega-3 fat supplementation on glucose metabolism and insulin in Mahabadi kid. METHODS: Twenty-eight Mahabad goat kids (3 to 4 months, with an average initial weight of 17 ± 5 kg) were randomly assigned to four dietary treatments with a 2 × 2 factorial arrangement, with 2 types of feeding frequency (twice or 4 times in a day) combined with 2 types of fat (saturated fat and fish oil in 2% of DM) to investigate the effect of omega-3 fat supplementation and feeding time frequency on glucose and insulin metabolism. Goats were fed individually for 90 days. On day 70 an intravenous glucose tolerance test was performed after 20 hours of food deprivation. Blood samples were collected at -15, -10, -5, 5, 10, 15, 20, 30, 45, 60, 120 and 180 min after glucose injection. Data were analyzed using the SAS GLM procedure. RESULTS: The IVGTT indicated that Omega-3 supplementation had a significant effect (p<0.05) on glucose clearance rate (CR). On the other hand, with increasing feeding frequency, kids had higher glucose clearance rate (K) and lower glucose half-life. CONCLUSIONS: The results suggested that dietary supplementation with omega-3 fat and increased feeding frequency of diet improved glucose and insulin metabolism. | ||
| کلیدواژه‌ها [English] | ||
| Omega 3, kid Mahabad, feeding frequency, Insulin sensitivity, glucose clearance rate | ||
| مراجع | ||
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