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NITROIMIDAZOLES XI [I]. SYNTHESES OF DISUBSTITUTED NITROIMIDAZOLYLQUINOLINES | ||
Journal of Sciences, Islamic Republic of Iran | ||
مقاله 5، دوره 6، شماره 1، خرداد 1995 اصل مقاله (351.59 K) | ||
چکیده | ||
Reaction of substituted-aniline (8) with ethyl (l-methyl-5-nitroimidazole-2- carbonyl) acetate (9) gave 4-hydroxy-2-(l-methyl-5-nitro-2-imidazolyl)- substituted-quinolines (lo), which were converted to compound 11 with phosphorus oxychloride. Substituted-2-(l-methyl-5-nitro-2-imidazo1yl)-4.- methyl-(or phenyl-) quinolines (14) were prepared through the reaction of 2- acetyl-5-nitro-1-methyl-imidazole (13) with 0-aminoacetophenones (or Oaminobenzophenones) in acid medium | ||
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