میز خدمت الکترونیک
دوره ویراستاری

  اخبار و اعلانات

 آمار

تعداد نشریات127
تعداد شماره‌ها7,196
تعداد مقالات77,227
تعداد مشاهده مقاله157,208,918
تعداد دریافت فایل اصل مقاله118,400,394
Raisi, Abbas, Rajabipour, Homayun, Taati, Majid, Norouzian, Hassan. (1405). Comparison of the effects of intraosseous and intramuscular injection of midazolam and its antagonist flumazenil in pigeons. , (), -. doi: 10.22059/ijvm.2026.408283.1005996
Abbas Raisi; Homayun Rajabipour; Majid Taati; Hassan Norouzian. "Comparison of the effects of intraosseous and intramuscular injection of midazolam and its antagonist flumazenil in pigeons". , , , 1405, -. doi: 10.22059/ijvm.2026.408283.1005996
Raisi, Abbas, Rajabipour, Homayun, Taati, Majid, Norouzian, Hassan. (1405). 'Comparison of the effects of intraosseous and intramuscular injection of midazolam and its antagonist flumazenil in pigeons', , (), pp. -. doi: 10.22059/ijvm.2026.408283.1005996
Raisi, Abbas, Rajabipour, Homayun, Taati, Majid, Norouzian, Hassan. Comparison of the effects of intraosseous and intramuscular injection of midazolam and its antagonist flumazenil in pigeons. , 1405; (): -. doi: 10.22059/ijvm.2026.408283.1005996

Comparison of the effects of intraosseous and intramuscular injection of midazolam and its antagonist flumazenil in pigeons

Iranian Journal of Veterinary Medicine
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 29 اردیبهشت 1405
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22059/ijvm.2026.408283.1005996
نویسندگان
Abbas Raisi1؛ Homayun Rajabipour2؛ Majid Taati* 3؛ Hassan Norouzian1
1Department of Clinical Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.
2Doctor of Veterinary Medicine, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.
3Department of Basic Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.
چکیده
Abstract
BACKGROUND: The application of sedation-anesthesia protocols is one of the key strategies in the veterinary clinical management of domestic and wild birds.

OBJECTIVE: The study focused on understanding the physiological effects of midazolam (5 mg/kg) given as intraosseous (IO) and intramuscular (IM) injections, as well as flumazenil (0.05 mg/kg), its antagonist, among pigeons.
METHODS: 24 healthy homing pigeons were randomly assigned to six groups. In the first, the only treatment was intramuscular midazolam injection (MIM). The second group was administered midazolam by intraosseous injection (MIO). In the third group, an intramuscular injection of midazolam was given, followed by intramuscular flumazenil (MIM-FIM). Group four received IM midazolam and IO flumazenil (MIM-FIO). In group five, both drugs were administered by the IO route (MIO-FIO). In Group Six, midazolam was given by IO injection and flumazenil by IM (MIO-FIM). The following parameters were assessed over 5, 10, and 15 minutes after the last injection: heart rate, respiration, and electrocardiogram (ECG).
RESULT: The findings indicate that the heart rate after 10 minutes of IO flumazenil administration was significantly higher than that of the MIO group (<0.05). The respiratory rate at 5 and 15 minutes in the MIO-FIO group was significantly higher than that of the MIO group(P<0.05). On ECG, T wave voltage at 15 minutes appeared quite distinct from that of the MIM-FIM group compared to the MIO-FIM group (P<0.05). It is concluded that both techniques of injecting midazolam provide good sedation without much reduction in heart rate and respiration, flumazenil is reversibly effective, and both methods induce a downward trend in vital signs, suggesting that IO is a little more efficacious than IM. CONCLUSIONS: Therefore, the findings indicated that IO and IM midazolam and flumazenil injections are safe and reversible in pigeons and yield favorable cardiac effects.
کلیدواژه‌ها
Flumazenil؛ Intramuscular؛ Intraosseous؛ Midazolam؛ Pigeon
آمار
تعداد مشاهده مقاله: 33





سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب