| تعداد نشریات | 127 |
| تعداد شمارهها | 7,237 |
| تعداد مقالات | 77,623 |
| تعداد مشاهده مقاله | 161,088,068 |
| تعداد دریافت فایل اصل مقاله | 120,787,408 |
تأثیر آلفا لیپوئیک اسید و منابع مختلف سلنیوم بر عملکرد رشد، ویژگیهای لاشه، ریخت شناسی روده و جمعیت میکروبی جوجههای گوشتی | ||
| علوم دامی ایران | ||
| دوره 57، شماره 2، تیر 1405، صفحه 315-331 اصل مقاله (1.39 M) | ||
| نوع مقاله: مقاله پژوهشی | ||
| شناسه دیجیتال (DOI): 10.22059/ijas.2025.404275.654100 | ||
| نویسندگان | ||
| محمد ولی منصور کیایی؛ وحید رضایی پور* ؛ سکینه اسدزاده؛ روح الله عبدالله پور؛ مهدی چوبچیان | ||
| گروه علوم دامی، دانشگاه آزاد اسلامی واحد قائمشهر ، قائمشهر، ایران | ||
| چکیده | ||
| این تحقیق به منظور تأثیر منابع مختلف سلنیوم (معدنی، آلی و نانو) و سطوح آلفا لیپوئیک اسید بر عملکرد رشد، ویژگیهای لاشه، ریختشناسی ژژنوم و جمعیت میکروبی روده جوجههای گوشتی انجام شد. در این آزمایش، تعداد 450 قطعه جوجه گوشتی نر سویه راس 308 در 6 تیمار و 5 تکرار استفاده شد. جیرههای آزمایشی در قالب یک طرح کاملا تصادفی و با آرایش فاکتوریل2×3 شامل استفاده از دو سطح آلفالیپوئیک اسید در جیره (صفر و 300 میلیگرم بر کیلوگرم) و سه نوع منبع سلنیوم جیره شامل منبع معدنی (سلنیت سدیم)، منبع آلی (سلنومتیونین) و منبع نانو (نانو سلنیوم) بودند. نتایج نشان داد که جوجههای تغذیه شده با سلنیوم آلی و نانو ضریب تبدیل غذایی بهتری نسبت به سلنیوم معدنی داشتند (P<0.05). همچنین، مصرف 300 میلیگرم آلفا لیپوئیک اسید موجب افزایش معنیدار وزن و بهبود ضریب تبدیل غذایی در جوجهها شد (P<0.05). استفاده از نانو سلنیوم در مقایسه با سلنیوم معدنی سبب افزایش درصد لاشه، ران، بورس و طحال شد (P<0.05). از طرفی، بیشترین وزن نسبی طحال در گروه ترکیبی نانو سلنیوم به همراه آلفا لیپوئیک مشاهده شد (P<0.05). در ریختشناسی ژژنوم، مصرف آلفا لیپوئیک اسید و استفاده از سلنیوم نانو به طور معنیداری طول و مساحت پرزهای ژژنوم را افزایش دادند (P<0.05). نتایج جمعیت میکروبی نشان داد که افزودن آلفا لیپوئیک اسید به جیره موجب افزایش جمعیت لاکتوباسیلوس در روده کور جوجهها شد (P<0.05). بنابراین میتوان نتیجهگیری کرد که استفاده از سلنیوم آلی و نانو و نیز آلفا لیپوئیک اسید سبب بهبود عملکرد رشد و سلامت روده جوجههای گوشتی شد. | ||
| کلیدواژهها | ||
| آلفا لیپوئیک اسید؛ جوجه گوشتی رشد؛ لاشه؛ سلنیوم | ||
| مراجع | ||
|
REFERENCES Abd El-Hack, M. E., Ashour, E. A., Baset, S. A., Kamal, M., Swelum, A. A., Suliman, G. M., & Bassiony, S. S. (2024). Effect of dietary supplementation of organic selenium nanoparticles on growth performance and carcass traits of broiler chickens. Biological trace element research, 202(8), 3760-3766. https://doi.org/10.1007/s12011-023-03948-x Ahmadi, M., Poorghasemi, M., Seidavi, A., Hatzigiannakis, E., & Milis, C. (2020). An optimum level of nano-selenium supplementation of a broiler diet according to the performance, economical parameters, plasma constituents and immunity. Journal of Elementology, 25(3), 1187-1198. https://doi.org/10.5601/jelem.2020.25.3.1904 Alian, H. A., Samy, H. M., Ibrahim, M. T., & Mahmoud, M. M. (2020). Nanoselenium effect on growth performance, carcass traits, antioxidant activity, and immune status of broilers. Environmental Science and Pollution Research, 27(31), 38607-38616. https://doi.org/10.1007/s11356-020-09660-4 Arnaut, P. R., da Silva Viana, G., da Fonseca, L., Alves, W. J., Muniz, J. C. L., Pettigrew, J. E., & Hannas, M. I. (2021). Selenium source and level on performance, selenium retention and biochemical responses of young broiler chicks. BMC veterinary research, 17(1), 151. https://doi.org/10.1186/s12917-021-02881-7 Arshad, M. S., Anjum, F. M., Khan, M. I., Shahid, M., Akhtar, S., & Sohaib, M. (2013). Wheat germ oil enrichment in broiler feed with α-lipoic acid to enhance the antioxidant potential and lipid stability of meat. Lipids in health and disease, 12(1), 164. https://doi.org/10.1186/1476-511X-12-164 Awad, A., Zaglool, A. W., Ahmed, S. A., & Khalil, S. R. (2019). Transcriptomic profile change, immunological response and disease resistance of Oreochromis niloticus fed with conventional and Nano-Zinc oxide dietary supplements. Fish & Shellfish Immunology, 93, 336-343. https://doi.org/10.1016/j.fsi.2019.04.016 Bakhshalinejad, R., Akbari Moghaddam Kakhki, R., & Zoidis, E. (2018). Effects of different dietary sources and levels of selenium supplements on growth performance, antioxidant status and immune parameters in Ross 308 broiler chickens. British Poultry Science, 59(1), 81-91. https://doi.org/10.1080/00071668.2017.1410102 Bień, D., Michalczuk, M., Szkopek, D., Kinsner, M., & Konieczka, P. (2022). Changes in lipids metabolism indices as a result of different form of selenium supplementation in chickens. Scientific Reports, 12(1), 13817. https://doi.org/10.1038/s41598-022-15868-3 Boostani, A., Sadeghi, A. A., Mousavi, S. N., Chamani, M., & Kashan, N. (2015). Effects of organic, inorganic, and nano-Se on growth performance, antioxidant capacity, cellular and humoral immune responses in broiler chickens exposed to oxidative stress. Livestock science, 178, 330-336. https://doi.org/10.1016/j.livsci.2015.06.019 Chen, P., Ma, Q. G., Ji, C., Zhang, J. Y., Zhao, L. H., Zhang, Y., & Jie, Y. Z. (2011). Dietary lipoic acid influences antioxidant capability and oxidative status of broilers. International journal of molecular sciences, 12(12), 8476-8488. https://doi.org/10.3390/ijms12128476 Dalia, A. M., Loh, T. C., Sazili, A. Q., & Samsudin, A. A. (2020). Influence of bacterial organic selenium on blood parameters, immune response, selenium retention and intestinal morphology of broiler chickens. BMC veterinary research, 16(1), 365. https://doi.org/10.1186/s12917-020-02715-2 Fisinin, V. I., Papazyan, T. T., & Surai, P. F. (2008). Selenium in poultry nutrition. In Current advances in selenium research and applications (pp. 221-261). Wageningen Academic. https://doi.org/10.3920/978-90-8686-741-0_10 Gangadoo, S., Dinev, I., Chapman, J., Hughes, R. J., Van, T. T. H., Moore, R. J., & Stanley, D. (2018). Selenium nanoparticles in poultry feed modify gut microbiota and increase abundance of Faecalibacterium prausnitzii. Applied microbiology and biotechnology, 102(3), 1455-1466. https://doi.org/10.1007/s00253-017-8687-4 Guo, Z. Y., Li, J. L., Zhang, L., Jiang, Y., Gao, F., & Zhou, G. H. (2014). Effects of alpha-lipoic acid supplementation in different stages on growth performance, antioxidant capacity and meat quality in broiler chickens. British poultry science, 55(5), 635-643. https://doi.org/10.1080/00071668.2014.924256 Huang, C. C., Sun, J., Ji, H., Oku, H., Chang, Z. G., Tian, J. J., & Xie, J. (2019). Influence of dietary alpha-lipoic acid and lipid level on the growth performance, food intake and gene expression of peripheral appetite regulating factors in juvenile grass carp (Ctenopharyngodon idellus). Aquaculture, 505, 412-422. https://doi.org/10.1016/j.aquaculture.2019.412422 Huang, H., Wang, Y., An, Y., Tian, Y., Li, S., & Teng, X. (2017). Selenium for the mitigation of toxicity induced by lead in chicken testes through regulating mRNA expressions of HSPs and selenoproteins. Environmental Science and Pollution Research, 24(16), 14312-14321. https://doi.org/10.1007/s11356-017-0319-4 Hosnedlova, B., Kepinska, M., Skalickova, S., Fernandez, C., Ruttkay-Nedecky, B., Peng, Q., & Kizek, R. (2018). Nano-selenium and its nanomedicine applications: a critical review. International journal of nanomedicine, 2107-2128. https://doi.org/10.2147/IJN.S157541 Hosseintabar-Ghasemabad, B., Kvan, O. V., Sheida, E. V., Bykov, A. V., Zigo, F., Seidavi, A., & Salem, A. Z. M. (2024). Nano selenium in broiler feeding: physiological roles and nutritional effects. AMB Express, 14(1), 117. https://doi.org/10.1186/s13568-024-01545-7 Hu, C. H., Li, Y. L., Xiong, L., Zhang, H. M., Song, J., & Xia, M. S. (2012). Comparative effects of nano elemental selenium and sodium selenite on selenium retention in broiler chickens. Animal feed science and technology, 177(3-4), 204-210. https://doi.org/10.1016/j.anifeedsci.2012.08.010 Kasaikina, M. V., Kravtsova, M. A., Lee, B. C., Seravalli, J., Peterson, D. A., Walter, J. & Gladyshev, V. N. (2011). Dietary selenium affects host selenoproteome expression by influencing the gut microbiota. The FASEB Journal, 25(7), 2492. https://doi.org/10.1096/fj.11-185218 Khan, I., Zaneb, H., Masood, S., Ashraf, S., Rehman, H. F., Tahir, S. K. & Shah, M. (2021). Supplementation of selenium nanoparticles-loaded chitosan improves production performance, intestinal morphology, and gut microflora in broiler chickens. The journal of poultry science, 59(3), 272-281. https://doi.org/10.2141/jpsa.0210026 Li, W., Wei, F., Xu, B., Sun, Q., Deng, W., Ma, H., & Li, S. (2019). Effect of stocking density and alpha-lipoic acid on the growth performance, physiological and oxidative stress and immune response of broilers. Asian-Australasian Journal of Animal Sciences, 32(12), 1914. https://doi.org/10.5713/ajas.19.0146 Liao, X., Lu, L., Li, S., Liu, S., Zhang, L., Wang, G., & Luo, X. (2012). Effects of selenium source and level on growth performance, tissue selenium concentrations, antioxidation, and immune functions of heat-stressed broilers. Biological Trace Element Research, 150(1), 158-165. https://doi.org/10.1007/s12011-012-9443-3 Lochi, G. M., Shah, M. G., Gandahi, J. A., Gadahi, J. A., Hadi, S. A., Farooq, T., & Rahmani, M. M. (2023). Effect of selenium nanoparticles and chitosan on production performance and antioxidant integrity of heat-stressed broiler. Biological Trace Element Research, 201(4), 1977-1986. https://doi.org/10.1007/s12011-023-02994 Lu, M., Bai, J., Wei, F., Xu, B., Sun, Q., Li, J., & Li, S. (2017). Effects of alpha‐lipoic acid supplementation on growth performance, antioxidant capacity and biochemical parameters for ammonia‐exposed broilers. Animal Science Journal, 88(8), 1220-1225. https://doi.org/10.1111/asj.12819 Ma, H., Xu, B., Li, W., Wei, F., Kim, W. K., Chen, C., & Li, S. (2020). Effects of alpha-lipoic acid on the behavior, serum indicators, and bone quality of broilers under stocking density stress. Poultry Science, 99(10), 4653-4661. https://doi.org/10.1016/j.psj.2020.05.012 Mohammadi, A., Ghazanfari, S., & Sharifi, S. D. (2019). Comparative effects of dietary organic, inorganic, and Nano-selenium complexes and rosemary essential oil on performance, meat quality and selenium deposition in muscles of broiler chickens. Livestock Science, 226, 21-30. https://doi.org/10.1016/j.psj.2020.05.012 Mohammadi, E., Janmohammadi, H., Olyayee, M., Helan, J. A., & Kalanaky, S. (2020). Nano selenium improves humoral immunity, growth performance and breast-muscle selenium concentration of broiler chickens. Animal Production Science, 60(16), 1902-1910. https://doi.org/10.1071/AN20186 Molan, A. L., Liu, Z., & Tiwari, R. (2010). The ability of green tea to positively modulate key markers of gastrointestinal function in rats. Phytotherapy Research, 24(11), 1614-1619. https://doi.org/10.1002/ptr.3207 Mousa, B. H., & Hamad, H. Y. (2022). Role of alpha lipoic acid and coenzyme (Q10) in productive performance of broiler. Indian Journal of Ecology, 49(18), 397-401. Oliveira, T. F. B., Rivera, D. F. R., Mesquita, F. R., Braga, H., Ramos, E. M., & Bertechini, A. G. (2014). Effect of different sources and levels of selenium on performance, meat quality, and tissue characteristics of broilers. Journal of Applied Poultry Research, 23(1), 15-22. https://doi.org/10.3382/japr.2013-00859 Packer, L. (1994). Antioxidant properties of lipoic acid and its therapeutic effects in prevention of diabetes complications and cataracts a. Annals of the New York Academy of Sciences, 738(1), 257-264. https://doi.org/10.1111/j.1749-6632.1994.tb23416.x Pappas, A. C., Zoidis, E., & Chadio, S. E. (2019). Maternal selenium and developmental programming. Antioxidants, 8(5), 145. https://doi.org/10.3390/antiox8050145 Sahin, Z., Ozkaya, A., Yilmaz, O., Yuce, A., & Gunes, M. (2017). Investigation of the role of α-lipoic acid on fatty acids profile, some minerals (zinc, copper, iron) and antioxidant activity against aluminum-induced oxidative stress in the liver of male rats. Journal of Basic and Clinical Physiology and Pharmacology, 28(4), 355-361. https://doi.org/10.1515/jbcpp-2016-0117 Sakamoto, K., Hirose, H., Onizuka, A., Hayashi, M., Futamura, N., Kawamura, Y., & Ezaki, T. (2000). Quantitative study of changes in intestinal morphology and mucus gel on total parenteral nutrition in rats. Journal of Surgical Research, 94(2), 99-106. Saleh, A. A. (2014). Effect of dietary mixture of Aspergillus probiotic and selenium nano-particles on growth, nutrient digestibilities, selected blood parameters and muscle fatty acid profile in broiler chickens. Anim Sci Pap Rep, 32(1), 65-79. Shi, C., Sun, Y., Zhang, X., Zheng, Z., Yang, M., Ben, H., & Xia, X. (2016). Antimicrobial effect of lipoic acid against Cronobacter sakazakii. Food Control, 59, 352-358. https://doi.org/10.1016/j.foodcont.2015.06.037 Sinha, M., Bir, A., Banerjee, A., Bhowmick, P., & Chakrabarti, S. (2016). Multiple mechanisms of age-dependent accumulation of amyloid beta protein in rat brain: Prevention by dietary supplementation with N-acetylcysteine, α-lipoic acid and α-tocopherol. Neurochemistry international, 95, 92-99. https://doi.org/10.1016/j.neuint.2015.12.009 Skalickova, S., Milosavljevic, V., Cihalova, K., Horky, P., Richtera, L., & Adam, V. (2017). Selenium nanoparticles as a nutritional supplement. Nutrition, 33, 83-90. https://doi.org/10.1016/j.nut.2016.08.011 Spalding, M. D., & Prigge, S. T. (2010). Lipoic acid metabolism in microbial pathogens. Microbiology and Molecular Biology Reviews, 74(2), 200-228. https://doi.org/10.1128/MMBR.00095-09 Srilatha, T., Reddy, V. R., Qudratullah, S., & Raju, M. V. L. N. (2010). Effect of alpha-lipoic acid and vitamin E in diet on the performance, antioxidation and immune response in broiler chicken. International Journal of Poultry Science, 9(7), 678-683. Surai, P. F., Kochish, I. I., Fisinin, V. I., & Velichko, O. A. (2018). Selenium in poultry nutrition: From sodium selenite to organic selenium sources. The journal of poultry science, 55(2), 79-93. https://doi.org/10.2141/jpsa.0170132 Wang, J., Clark, D. L., Jacobi, S. K., & Velleman, S. G. (2021). Effect of vitamin E and alpha lipoic acid on intestinal development associated with wooden breast myopathy in broilers. Poultry Science, 100(3), 100952. https://doi.org/10.1016/j.psj.2020.12.044 Wasti, S., Sah, N., Lee, C. N., Jha, R., & Mishra, B. (2021). Dietary supplementation of alpha-lipoic acid mitigates the negative effects of heat stress in broilers. PloS one, 16(7), e0254936. Woods, S. L., Sobolewska, S., Rose, S. P., Whiting, I. M., Blanchard, A., Ionescu, C., & Pirgozliev, V. (2020). Effect of feeding different sources of selenium on growth performance and antioxidant status of broilers. British Poultry Science, 61(3), 274-280. https://doi.org/10.1080/00071668.2019.1711026 Yang, X., Zhang, H., Pang, F., Zhang, L., Fu, T., Wang, L., & Gao, T. (2023). Effects of α-lipoic acid on growth performance, antioxidant capacity, and immune function in sheep. Journal of animal science, 101, skad092. https://doi.org/10.1093/jas/skad092 Zamani Moghaddam, A. K., Mehraei Hamzekolaei, M. H., Khajali, F., & Hassanpour, H. (2017). Role of selenium from different sources in prevention of pulmonary arterial hypertension syndrome in broiler chickens. Biological Trace Element Research, 180(1), 164-170. https://doi.org/10.1007/s12011-017-1039-9 Zhang, J., Xiao, F., Zhang, L., Wang, X., Lai, X., Shen, Y., & Hua, F. (2018). Alpha-lipoic acid preconditioning and ischaemic postconditioning synergistically protect rats from cerebral injury induced by ischemia and reperfusion partly via inhibition TLR4/MyD88/NF-κB signaling pathway. Cellular Physiology and Biochemistry, 51(3), 1448-1460. https://doi.org/10.1159/000495820 Zhou, X., & Wang, Y. J. P. S. (2011). Influence of dietary nano elemental selenium on growth performance, tissue selenium distribution, meat quality, and glutathione peroxidase activity in Guangxi Yellow chicken. Poultry Science, 90(3), 680-686. https://doi.org/10.3382/ps.2010-01002 | ||
|
آمار تعداد مشاهده مقاله: 146 تعداد دریافت فایل اصل مقاله: 63 |
||