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Ahmadi-hamedani, Mahmood, Bagherian, Zeinab. (1404). A Review of the Immature Reticulocyte Fraction and Reticulocyte Maturity Index in Evaluating Regenerative, Non-Regenerative, and Pre-Regenerative Anemias in Dogs and Cats. , (), -. doi: 10.22059/ijvm.2025.387265.1005711
Mahmood Ahmadi-hamedani; Zeinab Bagherian. "A Review of the Immature Reticulocyte Fraction and Reticulocyte Maturity Index in Evaluating Regenerative, Non-Regenerative, and Pre-Regenerative Anemias in Dogs and Cats". , , , 1404, -. doi: 10.22059/ijvm.2025.387265.1005711
Ahmadi-hamedani, Mahmood, Bagherian, Zeinab. (1404). 'A Review of the Immature Reticulocyte Fraction and Reticulocyte Maturity Index in Evaluating Regenerative, Non-Regenerative, and Pre-Regenerative Anemias in Dogs and Cats', , (), pp. -. doi: 10.22059/ijvm.2025.387265.1005711
Ahmadi-hamedani, Mahmood, Bagherian, Zeinab. A Review of the Immature Reticulocyte Fraction and Reticulocyte Maturity Index in Evaluating Regenerative, Non-Regenerative, and Pre-Regenerative Anemias in Dogs and Cats. , 1404; (): -. doi: 10.22059/ijvm.2025.387265.1005711

A Review of the Immature Reticulocyte Fraction and Reticulocyte Maturity Index in Evaluating Regenerative, Non-Regenerative, and Pre-Regenerative Anemias in Dogs and Cats

Iranian Journal of Veterinary Medicine
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 15 اردیبهشت 1404
نوع مقاله: Review article
شناسه دیجیتال (DOI): 10.22059/ijvm.2025.387265.1005711
نویسندگان
Mahmood Ahmadi-hamedani* 1؛ Zeinab Bagherian2
1Department of Clinical Sciences, Faculty of Veterinary Medicine, Semnan University, Semnan, Iran
2Student Research Committee, Faculty of Veterinary Medicine, Semnan University, Semnan, Iran
چکیده
Anemia is one of the most common hematological topics in dogs and cats, with various causes and outcomes. The immature reticulocyte fraction (IRF) and reticulocyte maturity index (RMI) serve as emerging indicators that identify highly immature reticulocytes containing large amounts of ribonucleic acid (RNA). These parameters are critical for the immediate evaluation of bone marrow response, the precise differential diagnosis of various causes of anemia, the examination of treatment efficacy, and the control of bone marrow regeneration in different healthcare settings. The maturity of reticulocytes and the RNA fluorescence intensity identified by systems such as Sysmex XN-1000V and ADVIA 2120i is how these hematology analyzers precisely calculate these indices. The IRF and RMI in dog and cat species with hemolytic anemias were significantly higher than those in hemorrhagic anemias. Additionally, these reticulocyte parameters in dogs and cats with bone marrow failure were considerably lower than in other non-regenerative anemias, and both groups compared to pre-regenerative anemias. This review article addresses the concepts, clinical applications, and comparison of the IRF and RMI determined by the Sysmex XN-1000V and ADVIA 2120i hematology analyzers in various types of regenerative, non-regenerative and pre-regenerative anemias in dogs and cats.
کلیدواژه‌ها
Blood Cell Regeneration؛ Bone Marrow Response؛ Diagnostic Indicators؛ RNA Fluorescence؛ Veterinary Medicine
آمار
تعداد مشاهده مقاله: 26





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