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A Brief Review of Synthesis Methods, Biological Activities and Cytotoxicity of Cerium Oxide Nanoparticles | ||
Iranian Journal of Veterinary Medicine | ||
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 11 اردیبهشت 1403 اصل مقاله (1.1 M) | ||
نوع مقاله: Review article | ||
شناسه دیجیتال (DOI): 10.22059/ijvm.2024.372683.1005519 | ||
نویسندگان | ||
behnaz karimi* 1؛ saman Yousefi2 | ||
1Department of Basic Science, Faculty of Veterinary Medicine, Shahrekord University, shahrekord, Iran | ||
2Department of Pathobiology, Faculty of Veterinary Medicine, Islamic Azad University, shahrekord, Iran | ||
چکیده | ||
Cerium oxide nanoparticles (CeO2-NPs, or nanoceria) are among the most unique and promising lanthanide nanomaterials, with unique properties such as their redox activity, oxygen storage capacity, and free radical scavenging ability. Their ability to self-regenerate their surface makes them a potential candidate in different fields, especially the biomedical division. The mechanisms by which nanoceria protect against oxidative stress include the direct scavenging of radicals by mimicking the catalytic activity of redox enzymes. Nanoceria can act as a double-edged sword and display both oxidant and antioxidant properties, depending on surface characteristics and the environment. In spite of their potential for clinical applications, there are also contradictory studies reporting the potential toxicity of CNPs. This review describes: (1) the methods of synthesis for CeO2-NPs; (2) the applications of nanoceria for antioxidant, anti-inflammatory, and anticancer activities, including the most recent studies carried out in vivo and in vitro; and (3) their cytotoxic activity. | ||
کلیدواژهها | ||
Cerium oxide nanoparticles؛ Nanoceria؛ Antioxidant؛ Synthesis؛ Cytotoxic activity | ||
آمار تعداد مشاهده مقاله: 72 تعداد دریافت فایل اصل مقاله: 190 |