تعداد نشریات | 161 |
تعداد شمارهها | 6,533 |
تعداد مقالات | 70,518 |
تعداد مشاهده مقاله | 124,133,294 |
تعداد دریافت فایل اصل مقاله | 97,239,314 |
Health impacts and functional properties of lycopenes: A Review | ||
Journal of Food and Bioprocess Engineering | ||
دوره 5، شماره 1، شهریور 2022، صفحه 24-33 اصل مقاله (705.52 K) | ||
نوع مقاله: Review article | ||
شناسه دیجیتال (DOI): 10.22059/jfabe.2022.336045.1104 | ||
نویسندگان | ||
Ali Motamedzadegan؛ Azita Nemati* | ||
Department of Food Science and Technology, Faculty of Agricultural Engineering, Sari Agricultural Sciences and Natural Resources University, Km 9 Farah Abad Road, Sari, Iran | ||
چکیده | ||
There is now a growing awareness of a healthy lifestyle in the community and people are looking for useful products in their diet. Functional foods are therefore of great importance to health. Lycopene is a carotenoid that causes the red color in fruits and vegetables. Lycopene is one of the most effective antioxidants among the carotenoids. Lycopene is synthesized by some plants and microorganisms and is the predominant carotenoid found in human serum, and as a pharmaceutical supplement, it protects important cell biomolecules - such as DNA, proteins and fats - from the oxidation and destruction of their radicals. It plays an important role in reducing the risk of cardiovascular diseases as well as treating metabolic syndrome, liver disease and cancers. In this article, the characteristics of lycopene and its effect on human health and treatment of diseases are reviewed. | ||
کلیدواژهها | ||
Antioxidant؛ Cancer؛ Carotenoid؛ Lycopene؛ Tomato | ||
مراجع | ||
Abdul-Hamid, M., & Salah, M. (2013). Lycopene reduces deltamethrin effects induced thyroid toxicity and DNA damage in albino rats. The Journal of Basic & Applied Zoology, 66, 155-163.
Agarwal, S., & Rao, A. V. (2000). Tomato lycopene and its role in human health and chronic diseases. Cmaj, 163, 739-744.
Agarwal, S., & Rao, Α. V. (2000). Carotenoids and chronic diseases. Drug metabolism and drug interactions, 17, 189-210.
Aizawa, K., Liu, C., Tang, S., Veeramachaneni, S., Hu, K. Q., Smith, D. E., & Wang, X. D. (2016). Tobacco carcinogen induces both lung cancer and non‐alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation. International journal of cancer, 139, 1171-1181.
Aktepe, O. H., Şahin, T. K., Güner, G., Arik, Z., & Yalçin, Ş. (2021). Lycopene sensitizes the cervical cancer cells to cisplatin via targeting nuclear factorkappa B (NF-𝛋B) pathway. Turkish journal of medical sciences, 51, 368-374.
Ardawi, M. S. M., Badawoud, M. H., Hassan, S. M., Rouzi, A. A., Ardawi, J. M., AlNosani, N. M., & Mousa, S. A. (2016). Lycopene treatment against loss of bone mass, microarchitecture and strength in relation to regulatory mechanisms in a postmenopausal osteoporosis model. Bone, 83, 127-140.
Baer-Dubowska, W., Bartoszek, A., & Malejka-Giganti, D. (Eds.). (2005). Carcinogenic and anticarcinogenic food components. CRC Press.
Bhuvaneswari, V., & Nagini, S. (2005). Lycopene: a review of its potential as an anticancer agent. Current Medicinal Chemistry-Anti-Cancer Agents, 5, 627-635.
Borguini, R. G., & Ferraz da Silva Torres, E. A. (2009). Tomatoes and tomato products as dietary sources of antioxidants. Food Reviews International, 25, 313-325.
Borel, P., Desmarchelier, C., Dumont, U., Halimi, C., Lairon, D., Page, D., & Remond, D.(2016). Dietary calcium impairs tomato lycopene bioavailability in healthy humans. British Journal of Nutrition, 116, 2091-2096.
Boileau, T. W. M., Boileau, A. C., & Erdman Jr, J. W. (2002). Bioavailability of all-trans and cis–Isomers of Lycopene. Experimental Biology and Medicine, 227, 914-919.
Boileau, T. W. M., Liao, Z., Kim, S., Lemeshow, S., Erdman, Jr, J. W., & Clinton, S. K. (2003). Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. Journal of the National Cancer Institute, 95, 1578-1586.
Bramley, P. M. (2000). Is lycopene beneficial to human health. Phytochemistry, 54, 233-236.
Bucak, M. N., Ataman, M. B., Başpınar, N., Uysal, O., Taşpınar, M., Bilgili, A., & Akal, E. (2015). Lycopene and resveratrol improve post‐thaw bull sperm parameters: sperm motility, mitochondrial activity and DNA integrity. Andrologia, 47, 545-552.
Camara, M., de Cortes Sánchez-Mata, M., Fernández-Ruiz, V., Cámara, R. M., Manzoor, S., & Caceres, J. O. (2013). Lycopene: A review of chemical and biological activity related to beneficial health effects. In Studies in natural products chemistry, 40, 383-426.
Chen, P., Zhang, W., Wang, X., Zhao, K., Negi, D. S., Zhuo, L., & Zhang, X. (2015). Lycopene and risk of prostate cancer: a systematic review and meta-analysis. Medicine, 94(33), e1260.
Chen, D., Huang, C., & Chen, Z. (2019). A review for the pharmacological effect of lycopene in central nervous system disorders. Biomedicine & Pharmacotherapy, 111, 791-801.
Cheng, J., Miller, B., Balbuena, E., & Eroglu, A. (2020). Lycopene protects against smoking-induced lung cancer by inducing base excision repair. Antioxidants, 9, 643.
Choksi, P. M., & Joshi, V. Y. (2007). A review on lycopene extraction, purification, stability and applications. International Journal of Food Properties, 10, 289-298.
Choudhari, S. M., & Ananthanarayan, L. (2007). Enzyme aided extraction of lycopene from tomato tissues. Food chemistry, 102, 77-81.
Ciriminna, R., Fidalgo, A., Meneguzzo, F., Ilharco, L. M., & Pagliaro, M. (2016). Lycopene: emerging production methods and applications of a valued carotenoid. ACS Sustainable Chemistry & Engineering, 4, 643-650.
Colle, I. J., Van Buggenhout, S., Lemmens, L., Van Loey, A. M., & Hendrickx, M. E. (2012). The type and quantity of lipids present during digestion influence the in vitro bioaccessibility of lycopene from raw tomato pulp. Food Research International, 45, 250-255.
Costa-Rodrigues, J., Fernandes, M. H., Pinho, O., & Monteiro, P. R. R. (2018). Modulation of human osteoclastogenesis and osteoblastogenesis by lycopene. The Journal of nutritional biochemistry, 57, 26-34.
Crowe-White, K. M., Phillips, T. A., & Ellis, A. C. (2019). Lycopene and cognitive function. Journal of nutritional science, 8, e20.
Edge, R., Boehm, F., & Truscott, T. G. (2016). Oxygen effect on protection of human lymphoid cells against free radicals by the carotenoid lycopene. Free Radical Biology and Medicine, 100, S96.
Egydio, J. A., Moraes, Â. M., & Rosa, P. T. (2010). Supercritical fluid extraction of lycopene from tomato juice and characterization of its antioxidation activity. The Journal of Supercritical Fluids, 54, 159-164.
El-Raey, M. A., Ibrahim, G. E., & Eldahshan, O. A. (2013). Lycopene and lutein; A review for their chemistry and medicinal uses. Journal of Pharmacognosy and Phytochemistry, 2(1), 245-254.
Faisal, W., O'Driscoll, C. M., & Griffin, B. T. (2010). Bioavailability of lycopene in the rat: the role of intestinal lymphatic transport. Journal of Pharmacy and Pharmacology, 62, 323-331.
Filipcikova, R., Oborna, I., Brezinova, J., Novotny, J., Wojewodka, G., De Sanctis, J. B., & Radzioch, D. (2015). Lycopene improves the distorted ratio between AA/DHA in the seminal plasma of infertile males and increases the likelihood of successful pregnancy. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 159, 77-82.
Fraser, G. E., Jacobsen, B. K., Knutsen, S. F., Mashchak, A., & Lloren, J. I. (2020). Tomato consumption and intake of lycopene as predictors of the incidence of prostate cancer: the Adventist Health Study-2. Cancer Causes & Control, 31, 341-351.
Fritsch, C., Staebler, A., Happel, A., Cubero Márquez, M. A., Aguiló-Aguayo, I., Abadias, M., & Suárez-Estrella, F. (2017). Processing, valorization and application of bio-waste derived compounds from potato, tomato, olive and cereals: A review. Sustainability, 9, 1492.
Goula, A. M., Adamopoulos, K. G., Chatzitakis, P. C., & Nikas, V. A. (2006). Prediction of lycopene degradation during a drying process of tomato pulp. Journal of Food Engineering, 74, 37-46.
Goel, S., & Ahmed, J. (2015). A comparative study on efficacy of different treatment modalities of oral submucous fibrosis evaluated by clinical staging in population of Southern Rajasthan. Journal of Cancer Research and Therapeutics, 11, 113-118.
Grabowska, M., Wawrzyniak, D., Rolle, K., Chomczyński, P., Oziewicz, S., Jurga, S., & Barciszewski, J. (2019). Let food be your medicine: Nutraceutical properties of lycopene. Food & function, 10, 3090-3102.
Han, H., & Qun, W. A. N. G. (2007). Study on the effect of ultrasonic on lycopene extraction. Journal of Science and Emerging Technologies, 8(11).
Hedayati, N., Naeini, M. B., Nezami, A., Hosseinzadeh, H., Wallace Hayes, A., Hosseini, S., & Karimi, G. (2019). Protective effect of lycopene against chemical and natural toxins: A review. BioFactors, 45, 5-23.
Hernández-Almanza, A., Montañez, J., Martínez, G., Aguilar-Jiménez, A., Contreras-Esquivel, J. C., & Aguilar, C. N. (2016). Lycopene: progress in microbial production. Trends in Food Science & Technology, 56, 142-148.
Huang, C. S., Liao, J. W., & Hu, M. L. (2008). Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice. The Journal of nutrition, 138, 538-543.
Huang, X., Gao, Y., Zhi, X., Ta, N., Jiang, H., & Zheng, J. (2016). Association between vitamin A, retinol and carotenoid intake and pancreatic cancer risk: Evidence from epidemiologic studies. Scientific reports, 6, 38936.
Huang, R. F. S., Wei, Y. J., Inbaraj, B. S., & Chen, B. H. (2015). Inhibition of colon cancer cell growth by nanoemulsion carrying gold nanoparticles and lycopene. International Journal of Nanomedicine, 10, 2823-2846.
Ip, B. C., Liu, C., Lichtenstein, A. H., von Lintig, J., & Wang, X. D. (2015). Lycopene and apo-10′-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9′, 10′-oxygenase knockout male mice. The Journal of nutrition, 145, 268-276.
Javanmardi, J., & Kubota, C. (2006). Variation of lycopene, antioxidant activity, total soluble solids and weight loss of tomato during postharvest storage. Postharvest biology and technology, 41, 151-155.
Jhou, B. Y., Song, T. Y., Lee, I., Hu, M. L., & Yang, N. C. (2017). Lycopene inhibits metastasis of human liver adenocarcinoma SK-Hep-1 cells by downregulation of NADPH oxidase 4 protein expression. Journal of Agricultural and Food Chemistry, 65, 6893-6903.
Juan, C., Oyarzún, B., Quezada, N., & del Valle, J. M. (2006). Solubility of carotenoid pigments (lycopene and astaxanthin) in supercritical carbon dioxide. Fluid Phase Equilibria, 247, 90-95.
Khodaiyan, F., Razavi, S. H., & Mousavi, S. M. (2008). Optimization of canthaxanthin production by Dietzia natronolimnaea HS-1 from cheese whey using statistical experimental methods. Biochemical Engineering Journal, 40, 415-422.
Kim, D. J., Takasuka, N., Kim, J. M., Sekine, K., Ota, T., Asamoto, M., & Tsuda, H. (1997). Chemoprevention by lycopene of mouse lung neoplasia after combined initiation treatment with DEN, MNU and DMH. Cancer letters, 120, 15-22.
Kohlmeier, L., Kark, J. D., Gomez-Gracia, E., Martin, B. C., Steck, S. E., Kardinaal, A. F.,& Martin-Moreno, J. M. (1997). Lycopene and myocardial infarction risk in the EURAMIC Study. American Journal of Epidemiology, 146, 618-626.
Kong, K. W., Khoo, H. E., Prasad, K. N., Ismail, A., Tan, C. P., & Rajab, N. F. (2010). Revealing the power of the natural red pigment lycopene. Molecules, 15, 959-987.
Koul, A., Bansal, M. P., Aniqa, A., Chaudhary, H., & Chugh, N. A. (2019). Lycopene enriched tomato extract suppresses chemically induced skin tumorigenesis in mice. International Journal for Vitamin and Nutrition Research, 90(5-6).
Krebbers, B., Matser, A. M., Hoogerwerf, S. W., Moezelaar, R., Tomassen, M. M., & van den Berg, R. W. (2003). Combined high-pressure and thermal treatments for processing of tomato puree: evaluation of microbial inactivation and quality parameters. Innovative Food Science & Emerging Technologies, 4, 377-385.
Kun, Y., Ssonko Lule, U., & Xiao-Lin, D. (2006). Lycopene: Its properties and relationship to human health. Food Reviews International, 22, 309-333.
Lianfu, Z., & Zelong, L. (2008). Optimization and comparison of ultrasound/microwave assisted extraction (UMAE) and ultrasonic assisted extraction (UAE) of lycopene from tomatoes. Ultrasonics Sonochemistry, 15, 731-737.
Lim, S., Hwang, S., Yu, J. H., Lim, J. W., & Kim, H. (2017). Lycopene inhibits regulator of calcineurin 1‐mediated apoptosis by reducing oxidative stress and down‐regulating Nucling in neuronal cells. Molecular Nutrition & Food Research, 61, 1600530.
Li, X., & Xu, J. (2014). Meta-analysis of the association between dietary lycopene intake and ovarian cancer risk in postmenopausal women. Scientific reports, 4, 4885.
Li, H., Deng, Z., Zhu, H., Hu, C., Liu, R., Young, J. C., & Tsao, R. (2012). Highly pigmented vegetables: Anthocyanin compositions and their role in antioxidant activities. Food research international, 46, 250-259.
Lopez-Jornet, P., Gómez-García, F., Carrillo, N. G., Valle-Rodríguez, E., Xerafin, A., & Vicente-Ortega, V. (2016). Radioprotective effects of lycopene and curcumin during local irradiation of parotid glands in Sprague Dawley rats. British Journal of Oral and Maxillofacial Surgery, 54, 275-279.
Mantzouridou, F., & Tsimidou, M. Z. (2008). Lycopene formation in Blakeslea trispora. Chemical aspects of a bioprocess. Trends in food science & technology, 19, 363-371.
Matthäus, F., Ketelhot, M., Gatter, M., & Barth, G. (2014). Production of lycopene in the non-carotenoid-producing yeast Yarrowia lipolytica. Applied and Environmental Microbiology, 80, 1660-1669.
Miziorko, H. M. (2011). Enzymes of the mevalonate pathway of isoprenoid biosynthesis. Archives of biochemistry and biophysics, 505, 131-143.
Mohanty, N. K., Kumar, S., Jha, A. K., & Arora, R. P. (2001). Management of idiopathic oligoasthenospermia with lycopene. Indian journal of urology, 18, 57-61.
Mohanty, N. K., Saxena, S., Singh, U. P., Goyal, N. K., & Arora, R. P. (2005), Lycopene as a chemopreventive agent in the treatment of high-grade prostate intraepithelial neoplasia. In Urologic Oncology: Seminars and Original Investigations, 23, 383-385.
Motamedzadegan, A., & Tabarestani, H. S. (2018). Tomato Production, Processing, and Nutrition. Handbook of Vegetables and Vegetable Processing, 839-861.
Müller, L., Caris-Veyrat, C., Lowe, G., & Böhm, V. (2016). Lycopene and its antioxidant role in the prevention of cardiovascular diseases a critical review. Critical Reviews in Food Science and Nutrition, 56, 1868-1879.
Otles, S, & Cagindi., O. (2008). Carotenoids as natural colorants. In: food colorants: chemicaland functional properties edited by Socaciu, C.CRC Press, Boca Raton, FL.
Özkan, E., Akyüz, C., Dulundu, E., Topaloğlu, Ü., Şehirli, A. Ö., Ercan, F., & Şener, G. (2012). Protective effects of lycopene on cerulein-induced experimental acute pancreatitis in rats. Journal of Surgical Research, 176, 232-238.
Paredes-Lopez, O, & Osuna-Castro., J. A. (2007). Molecular biotechnology for nutraceuticalenrichment of food crops in: functional foods and biotechnology edited by Shetty, K., et al. CRC Press.Boca Raton, FL.
Paur, I., Lilleby, W., Bohn, S. K., Hulander, E., Klein, W., Vlatkovic, L., & Taskén, K. A. (2017). Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA. Clinical Nutrition, 36, 672-679.
Perveen, R., Suleria, H. A. R., Anjum, F. M., Butt, M. S., Pasha, I., & Ahmad, S. (2015). Tomato (Solanum lycopersicum) carotenoids and lycopenes chemistry; metabolism, absorption, nutrition, and allied health claims—A comprehensive review. Critical reviews in food science and nutrition, 55, 919-929.
Porrini, M., & Riso, P. (2000). Lymphocyte lycopene concentration and DNA protection from oxidative damage is increased in women after a short period of tomato consumption. The Journal of nutrition, 130, 189-192.
Preedy, V. R, & Watson., R. R. (2008). Lycopene nutritional, medicinal and therapeutic properties.Science Publishers, Enfield, NH, USA.
Prema, A., Janakiraman, U., Manivasagam, T., & Thenmozhi, A. J. (2015). Neuroprotective effect of lycopene against MPTP induced experimental Parkinson’s disease in mice. Neuroscience letters, 599, 12-19.
Qiu, W., Jiang, H., Wang, H., & Gao, Y. (2006). Effect of high hydrostatic pressure on lycopene stability. Food Chemistry, 97, 516-523.
Ranjbar, A., Ranjbar, E., Salimi, A. (2019). The role of lycopene in human health as a natural colorant. Nutrition & Food Science, 49, 284-298.
Reboul, E., Richelle, M., Perrot, E., Desmoulins-Malezet, C., Pirisi, V., & Borel, P. (2006). Bioaccessibility of carotenoids and vitamin E from their main dietary sources. Journal of Agricultural and Food Chemistry, 54, 8749-8755.
Saini, R. K., Rengasamy, K. R., Mahomoodally, F. M., & Keum, Y. S. (2020). Protective effects of lycopene in cancer, cardiovascular, and neurodegenerative diseases: An update on epidemiological and mechanistic perspectives. Pharmacological research, 155, 104730.
Sahlin, E., Savage, G. P., & Lister, C. E. (2004). Investigation of the antioxidant properties of tomatoes after processing. Journal of Food composition and Analysis, 17, 635-647.
Sahin, K., Cross, B., Sahin, N., Ciccone, K., Suleiman, S., Osunkoya, A. O., & Bilir, B. (2015). Lycopene in the prevention of renal cell cancer in the TSC2 mutant Eker rat model. Archives of biochemistry and biophysics, 572, 36-39.
Sahin, E. D., Yalcın, S., Ozercan, I. H., Kaygusuz, I., Karlıdag, T., Keles, E., & Akyigit, A. (2015). The effect of lycopene on experimental myringosclerosis. International journal of pediatric otorhinolaryngology, 79, 342-348.
Sahin, K., Gencoglu, H., Bilir, B., & Kucuk, O. (2018). Protective role of lycopene against oxidative stress in liver. In The Liver (pp. 155-167). Academic Press.
Sánchez-Moreno, C., Plaza, L., de Ancos, B., & Cano, M. P. (2003). Vitamin C, provitamin A carotenoids, and other carotenoids in high-pressurized orange juice during refrigerated storage. Journal of Agricultural and Food Chemistry, 51, 647-653.
Schneider, T., Graeff-Hönninger, S., French, W. T., Hernandez, R., Merkt, N., Claupein, W., & Pham, P. (2013). Lipid and carotenoid production by oleaginous red yeast Rhodotorula glutinis cultivated on brewery effluents. Energy, 61, 34-43.
Sen, S. (2019). The chemistry and biology of lycopene: antioxidant for human health. International Journal of Advancement in Life Sciences Research, 2, 08-14.
Shi, J., & Maguer, M. L. (2000). Lycopene in tomatoes: chemical and physical properties affected by food processing. Critical reviews in food science and nutrition, 40, 1-42.
Shi, J., Dai, Y., Kakuda, Y., Mittal, G., & Xue, S. J. (2008). Effect of heating and exposure to light on the stability of lycopene in tomato purée. Food control, 19, 514-520.
Silva, Y. P., Ferreira, T. A., Jiao, G., & Brooks, M. S. (2019). Sustainable approach for lycopene extraction from tomato processing by-product using hydrophobic eutectic solvents. Journal of food science and technology, 56, 1649-1654.
Singh, A., Neupane, Y. R., Panda, B. P., & Kohli, K. (2017). Lipid Based nanoformulation of lycopene improves oral delivery: formulation optimization, ex vivo assessment and its efficacy against breast cancer. Journal of microencapsulation, 34, 416-429
Singh, P., & Goyal, G. K. (2008). Dietary lycopene: Its properties and anticarcinogenic effects. Comprehensive Reviews in Food Science and Food Safety, 7, 255-270.
Siva, R., Palackan, M. G., Maimoon, L., Geetha, T., Bhakta, D., Balamurugan, P., & Rajanarayanan, S. (2011). Evaluation of antibacterial, antifungal, and antioxidant properties of some food dyes. Food Science and Biotechnology, 20, 7-13.
Srivastava, S., & Srivastava, A. K. (2015). Lycopene; chemistry, biosynthesis, metabolism and degradation under various abiotic parameters. Journal of Food Science and Technology, 52, 41-53.
Strazzullo, G., De Giulio, A., Tommonaro, G., La Pastina, C., Poli, A., Nicolaus, B., & Saturnino, C. (2007). Antioxidative activity and lycopene and β-carotene contents in different cultivars of tomato (Lycopersicon esculentum). International Journal of Food Properties, 10, 321-329.
Stahl, W. (2006).Tomato lycopene in photoprotection and skin care. In: Rao AV, editor, Tomatoes, lycopene and human health. Scotland: Caledonian Science Press. 199-211.
Svelander, C. A., Lopez‐Sanchez, P., Pudney, P. D., Schumm, S., & Alminger, M. A. (2007). High pressure homogenization increases the in vitro bioaccessibility of α‐and β‐carotene in carrot emulsions but not of lycopene in tomato emulsions. Journal of Food Science, 76, 215-225.
Tibäck, E. A., Svelander, C. A., Colle, I. J., Altskär, A. I., Alminger, M. A., Hendrickx, M. E., & Langton, M. I. (2009). Mechanical and thermal pretreatments of crushed tomatoes: effects on consistency and in vitro accessibility of lycopene. Journal of food science, 74, 386-395.
Toor, R. K., & Savage, G. P. (2005). Antioxidant activity in different fractions of tomatoes. Food research international, 38, 487494.
Vasconcelos, A. G., Valim, M. O., Amorim, A. G., do Amaral, C. P., de Almeida, M. P., Borges, T. K.,& Leite, J. R. S. (2020). Cytotoxic activity of poly-ɛ-caprolactone lipid-core nanocapsules loaded with lycopene-rich extract from red guava (Psidium guajava L.) on breast cancer cells. Food Research International, 136, 109548.
Verma, S., Sharma, A., Kumar, R., Kaur, C., Arora, A., Shah, R., & Nain, L. (2015). Improvement of antioxidant and defense properties of tomato (var. Pusa Rohini) by application of bioaugmented compost. Saudi journal of biological sciences, 22, 256-264.
Viuda-Martos, M., Sanchez-Zapata, E., Sayas-Barberá, E., Sendra, E., Pérez-Álvarez, J. A., & Fernández-López, J. (2014). Tomato and tomato byproducts. Human health benefits of lycopene and its application to meat products: a review. Critical reviews in food science and nutrition, 54(8), 1032-1049.
Wang, X. D. (2012). Lycopene metabolism and its biological significance. The American journal of clinical nutrition, 96, 1214-1222.
Wang, Q., Feng, L. R., Luo, W., Li, H. G., Zhou, Y., & Yu, X. B. (2015). Effect of inoculation process on lycopene production by Blakeslea trispora in a stirred-tank reactor. Applied biochemistry and biotechnology, 175, 770-779.
Wang, Z., Fan, J., Wang, J., Li, Y., Xiao, L., Duan, D., & Wang, Q. (2016). Protective effect of lycopene on high-fat diet-induced cognitive impairment in rats. Neuroscience Letters, 627, 185-191.
Wang, Y., Smith, S., Teichtahl, A. J., Hodge, A. M., Wluka, A. E., Giles, G. G., & Cicuttini, F. M. (2016). Association between dietary intake of antioxidants and prevalence of femoral head cartilage defects and bone marrow lesions in community-based adults. The Journal of rheumatology, 43, 1885-1890.
Wu, A., Liu, R., Dai, W., Jie, Y., Yu, G., Fan, X., & Huang, Q. (2015). Lycopene attenuates early brain injury and inflammation following subarachnoid hemorrhage in rats. International journal of clinical and experimental medicine, 8, 14316-14322.
Xi, J. (2006). Effect of high pressure processing on the extraction of lycopene in tomato paste waste. Chemical Engineering & Technology: Industrial Chemistry‐Plant Equipment‐Process Engineering‐Biotechnology, 29, 736-739.
Xu, X., Xie, B., Li, S., Wang, S., Xia, D., & Meng, H. (2021). Association of dietary tomato intake with bladder cancer risk in a prospective cohort of 101,683 individuals with 12.5 years of follow-up. Aging (Albany NY), 13(13), 17629- 17637.
Yi, C., Shi, J., Xue, S. J., Jiang, Y., & Li, D. (2009). Effects of supercritical fluid extraction parameters on lycopene yield and antioxidant activity. Food chemistry, 113, 1088-1094.
Zhang, Z. Q., Cao, W. T., Liu, J., Cao, Y., Su, Y. X., & Chen, Y. M. (2016). Greater serum carotenoid concentration associated with higher bone mineral density in Chinese adults. Osteoporosis International, 27, 1593-1601.
Zhao, W., Sun, Y., Cheng, Y., Ma, Y., & Zhao, X. (2019). Effect of high‐pressure carbon dioxide on the quality of cold‐and hot‐break tomato pulps. Journal of Food Processing and Preservation, 43, 13959.
Zuknik, M. H., Norulaini, N. N., & Omar, A. M. (2012). Supercritical carbon dioxide extraction of lycopene: A review. Journal of food engineering, 112, 253-262. | ||
آمار تعداد مشاهده مقاله: 349 تعداد دریافت فایل اصل مقاله: 228 |