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تأثیر تمرین تناوبی با شدت بالا بر مقادیر سرمی عامل رشد فیبروبلاست 21، مقاومت به انسولین و پروفایل لیپیدی در زنان چاق غیرفعال | ||
| نشریه علوم زیستی ورزشی | ||
| مقاله 5، دوره 10، شماره 4، اسفند 1397، صفحه 449-464 اصل مقاله (268.98 K) | ||
| نوع مقاله: مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I | ||
| شناسه دیجیتال (DOI): 10.22059/jsb.2018.245057.1216 | ||
| نویسندگان | ||
| جواد طلوعی آذر1؛ اصغر توفیقی* 2؛ رقیه علیزاده3 | ||
| 1استادیار فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه ارومیه، ارومیه، ایران. | ||
| 2دانشیار فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه ارومیه، ارومیه، ایران. | ||
| 3کارشناسی ارشد فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه ارومیه، ارومیه، ایران. | ||
| چکیده | ||
| عامل رشد فیبروبلاست 21 (FGF21) از هورمون‌های متابولیسمی بدن است که از بافت‌های مختلف ترشح می‌شود و در متابولیسم کربوهیدرات و لیپید نقش دارد و به بهبود همئوستاز گلوکز، پارامترهای چربی و کاهش وزن منجر می‌شود. بنابراین، هدف پژوهش حاضر بررسی تأثیر هشت هفته تمرین تناوبی با شدت بالا (HIIT) بر مقادیر سرمی FGF21، پروفایل لیپیدی و مقاومت به انسولین زنان چاق غیرفعال بود. 20 زن چاق غیرفعال (میانگین سن 96/2 ± 15/30 سال و BMI 27/1 ± 34/30 Kg/m2) به‌طور تصادفی در دو گروه 10 نفری HIIT و کنترل، داوطلب شرکت در پژوهش حاضر شدند. برنامۀ تمرین HIIT به مدت هشت هفته، سه جلسه در هفته و با شدت 90 درصد ضربان قلب هدف اجرا شد. داده‌های پژوهش با استفاده از آزمون آماریt همبسته وt مستقل در سطح معناداری 05/0P< تجزیه‌وتحلیل شدند. نتایج تحلیل آماری نشان داد برنامۀ تمرین HIIT به‌طور معناداری مقادیر سرمی FGF21 و HDL-Cزنان چاق غیرفعال را افزایش (05/0P<) و به‌طور معناداری مقاومت به انسولین، گلوکز، انسولین، کلسترول تام، تری‌گلیسیرید، CO/HDLرا کاهش داد. همچنین، نتایج آزمونt مستقل نشان داد بین تمرین HIIT و کنترل در مقادیر FGF21 و گلوکز تفاوت معناداری وجود دارد (05/0P<).براساس نتایج پژوهش حاضر، به‌نظر می‌رسد تمرین HIIT با افزایش مقادیر FGF21ممکن است نقش مؤثری در همئوستاز گلوکز، کاهش تودۀ چربی و افزایش مصرف انرژی داشته باشد و برای پیشگیری از چاقی و بهبود شاخص مقاومت به انسولین مورد توجه قرار گیرد. | ||
| کلیدواژه‌ها | ||
| پروفایل لیپیدی؛ تمرین تناوبی با شدت بالا؛ زنان چاق غیرفعال؛ مقاومت به انسولین؛ FGF21 | ||
| عنوان مقاله [English] | ||
| The Effect of High Intensity Interval Training on Serum Levels of FGF21, Insulin Resistance and Lipid Profile in Sedentary Obese Women | ||
| نویسندگان [English] | ||
| Javad Toloueiazar1؛ Asghar Tofighi2؛ Rogayhe Alizadeh3 | ||
| 1Assistant Professor of exercise physiology, Faculty of Sport Sciences, Urmia University, Urmia, Iran | ||
| 2Associate Professor of exercise Physiology, Faculty of Sport Sciences, Urmia University, Urmia, Iran | ||
| 3M.Sc. of exercise physiology, Faculty of Sport Sciences, Urmia University, Urmia, Iran. | ||
| چکیده [English] | ||
| Fibroblast growth factor 21 (FGF21) is one of the metabolism hormones which is secreted from different tissues, plays a role in carbohydrate and lipid metabolism and improves glucose hemostasis, fat parameters and weight loss. Thus, the aim of this study was to investigate the effect of 8 weeks of high intensity interval training (HIIT) on serum levels of FGF21, lipid profile and insulin resistance in sedentary obese women. 20 sedentary obese women (mean age 30.15±2.96 years and BMI 30.34±1.27 Kg/m2) volunteered to participate in the study and were randomly assigned to HIIT and control groups (each group 10 subjects). HIIT program was conducted for 8 weeks, 3 sessions each week with 90% target heart rate. The research data were analyzed by independent and dependent t tests at P<0.05. The results of the statistical analysis showed that HIIT program significantly increased serum levels of FGF21 and HLD-C (P<0.05) and significantly decreased insulin resistance, glucose, insulin, total cholesterol, triglyceride and CO/HDL in sedentary obese women. Also, the results of independent t test showed a significant difference between HIIT and control groups in FGF21 and glucose levels (P<0.05). According to the results of this study, it seems that high intensity interval training (HIIT) may play an influential role in glucose hemostasis, decreasing fat mass, and increasing energy expenditure through an increase in FGF21 levels and therefore may be considered to prevent obesity and improve insulin resistance marker. | ||
| کلیدواژه‌ها [English] | ||
| FGF21, high intensity interval training, insulin resistance, lipid profile, sedentary obese women | ||
| مراجع | ||
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