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مقصودی, صابر محمد, مهربانی یگانه, حسن, نجاتی جوارمی, اردشیر. (1397). شناسایی نواحی تحت انتخاب مثبت در ژنگان اسب‌های کرد و عرب ایرانی با استفاده از روش مبتنی بر نامتعادلی پیوستگی ژنی. , 49(2), 321-333. doi: 10.22059/ijas.2018.259151.653640
صابر محمد مقصودی; حسن مهربانی یگانه; اردشیر نجاتی جوارمی. "شناسایی نواحی تحت انتخاب مثبت در ژنگان اسب‌های کرد و عرب ایرانی با استفاده از روش مبتنی بر نامتعادلی پیوستگی ژنی". , 49, 2, 1397, 321-333. doi: 10.22059/ijas.2018.259151.653640
مقصودی, صابر محمد, مهربانی یگانه, حسن, نجاتی جوارمی, اردشیر. (1397). 'شناسایی نواحی تحت انتخاب مثبت در ژنگان اسب‌های کرد و عرب ایرانی با استفاده از روش مبتنی بر نامتعادلی پیوستگی ژنی', , 49(2), pp. 321-333. doi: 10.22059/ijas.2018.259151.653640
مقصودی, صابر محمد, مهربانی یگانه, حسن, نجاتی جوارمی, اردشیر. شناسایی نواحی تحت انتخاب مثبت در ژنگان اسب‌های کرد و عرب ایرانی با استفاده از روش مبتنی بر نامتعادلی پیوستگی ژنی. , 1397; 49(2): 321-333. doi: 10.22059/ijas.2018.259151.653640

شناسایی نواحی تحت انتخاب مثبت در ژنگان اسب‌های کرد و عرب ایرانی با استفاده از روش مبتنی بر نامتعادلی پیوستگی ژنی

علوم دامی ایران
مقاله 14، دوره 49، شماره 2، شهریور 1397، صفحه 321-333    اصل مقاله (635.42 K)
نوع مقاله: مقاله پژوهشی
شناسه دیجیتال (DOI): 10.22059/ijas.2018.259151.653640
نویسندگان
صابر محمد مقصودی1؛ حسن مهربانی یگانه* 2؛ اردشیر نجاتی جوارمی3
1دانشجوی دکتری، پردیس کشاورزی و منابع طبیعی دانشگاه تهران، کرج
2دانشیار، پردیس کشاورزی و منابع طبیعی دانشگاه تهران، کرج
3استاد، پردیس کشاورزی و منابع طبیعی دانشگاه تهران، کرج
چکیده
اسب­های عرب به داشتن عملکرد خوب در مسابقه‌های استقامتی، پرش و زیبایی شهرت دارند. اسب­های کرد بومی منطقه‌های کوهستانی غرب ایران، مناسب مسابقه‌های چوگان هستند. اسب­های کرد، قد کوتاه­تر و وزن سنگین­تری نسبت به اسب­های عرب دارند. در این بررسی آمارۀ XP-EHH که مبتنی بر نامتعادلی پیوستگی ژنی (لینکاژی) است برای شناسایی قطعه‌های کروموزومی تحت انتخاب در ژنگان (ژنوم) اسب­های کرد و عرب ایرانی استفاده شد. برای این منظور، از نمونۀ خون و مو 38 اسب عرب و 58 اسب کرد DNA ژنگانی استخراج شد. همۀ نمونه­ها DNA توسط آرایۀ Axiom MNEC670 تعیین نژادگان (ژنوتیپ) شدند. پس از پالایش داده‌ها آمارۀ XP-EHH محاسبه شد. در اسب­های عرب 51 جایگاه (85 ژن) و در اسب‌های کرد 7 جایگاه (13 ژن) تحت انتخاب شناسایی شد. نواحی تحت انتخاب در اسب­های عرب با مسیرهای درگیر در سامانۀ ایمنی، تشکیل پروتئین شیر، رشد و نمو و سوخت‌وساز (متابولیسم) ماهیچه، بینایی، شبکۀ عصبی و اندازۀ بدن مرتبط بودند درحالی‌که در اسب­های کرد با مسیر گیرندۀ جفت‌شونده با پروتئین G، رشد و بلوغ فیبرهای ماهیچه، تنظیم خون بندآوری (هموستازی) اکسیژن یاخته‌ای، رنگدانه­سازی در پوست و مو ارتباط داشتند.
کلیدواژه‌ها
اسب عرب ایرانی؛ نژاد اسب کرد؛ XP-EHH؛ نشانه‌های انتخاب
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